Is opposition to genetically modified food merely Luddism?

In and of itself, I do not see evidence that GMO foods are hazardous to human or animal health. What is hazardous is the fact that GMO seeds do not reproduce and force the annual repurchase of seed at great cost to food producers and to the detriment of the consumer. The worry is what happens when only global agri-businesses are allowed to grow and price food? We are now one step closer since this premise was recently up-held by the US Supreme Court when farmers challenged Monsanto’s GMO seed monopoly.